Eurasian Journal of Medical and Natural Sciences 4-jild 3-son (2024) · 240–256-betlar

ADVANCES IN THE HUMAN SKIN MICROBIOTA AND ITS ROLES IN CUTANEOUS DISEASES

Khujaeva, Shakhnoz

DOI: 10.5281/zenodo.10897699 · Manbada o'qish →

Annotatsiya

The skin, the body's largest organ, is influenced by environmental factors and is susceptible to various diseases, including acne, psoriasis, and atopic dermatitis. Serving as the primary barrier against pathogens, the skin's health is intricately linked to its microbiota. Despite the challenging conditions it presents, the human skin hosts a diverse array of commensal microorganisms that contribute to its overall environment. Imbalances and dysbiosis in the skin microbiota can lead to the onset or exacerbation of skin diseases. This review explores recent advancements in our understanding of the skin microbiota and its interactions with the human skin. Additionally, it examines the potential roles of specific microbial species in skin health and disease. The review delves into various strategies for preventing, diagnosing, and treating microbe-related skin conditions, such as adopting healthy diets, lifestyles, and the use of probiotics and prebiotics. Furthermore, it discusses the potential of synthetic biology to modulate the skin microbiota, offering opportunities to optimize interactions between microbes and the skin. Ultimately, this review sheds light on the recovery of the human skin microbiota, its connection to skin diseases, and innovative strategies for engineering or reconstructing it.

Skin, Microbiota, Commensal microbes, Synthetic biology, Omics technologies, Host-skin microbiota interaction, Cutaneous diseases, Acne.

Metadata manbasi: jurnal OAI-PMH arxivi · Sindex to'liq matnni saqlamaydi, manbaga havola beradi.