Eurasian Journal of Medical and Natural Sciences 6-jild 4-son (2026) · 127–132-betlar

CLINICAL AND FUNCTIONAL EFFECTIVENESS OF HELICOBACTER PYLORI ERADICATION THERAPY IN ADOLESCENTS

Исламова, Дильбар, Ибрагимова, Юлдуз, Тураева, Дилафруз, Кодирова, Шахло

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Annotatsiya

The study evaluated H. pylori eradication therapy in adolescents. The relevance is due to high prevalence and increasing antibiotic resistance. The aim was to compare triple and bismuth-based quadruple therapy. A total of 73 patients aged 14–18 years were included. Diagnosis included urea breath test, endoscopy, and pH-metry. Patients were divided into two treatment groups. Efficacy was assessed 4–6 weeks after therapy. Eradication rates were 83.3% and 93.3% respectively. Quadruple therapy provided faster symptom relief. More pronounced improvement in intragastric pH was observed. Differences in clinical and pH outcomes were significant (p<0.05). Quadruple therapy showed higher overall clinical effectiveness.

Helicobacter pylori, eradication, clinical and functional effectiveness, children.Helicobacter pylori, эрадикация, клинико-функциональная эффективность, детиHelicobacter pylori, eradikatsiya, klinik-funksional samaradorlik, bolalar.

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