Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali 3-jild 1-son (2022)
EFFICACY OF AMLODIPINE IN ARTERIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUS
Норматов Мурод Бурибаевич
Annotatsiya
The combination of AH and diabetes increases the risk of coronary heart disease, stroke, kidney failure by 2-3 times. Therefore, it is extremely important to recognize and diagnose both arterial hypertension and diabetes mellitus early, to prescribe the appropriate treatment in time and stop the development of severe vascular complications. On the ionic level, insulin affects the entry of calcium and sodium into the cell, which affect the contractility of vascular smooth muscle fibers. As a result of decreased insulin sensitivity, calcium influx into the cell increases and smooth muscle cell tension increases. In such patients, the response of coronary arteries to physiological stimuli is reduced (decreased ability to dilate), which leads to impaired microcirculation.
Артериальная гипертензия, амлодипин, сахарный диабет 2 типаArterial hypertension, amlodipine, type 2 diabetes mellitusArterial gipertenziya, amlodipin, qandli diabet 2-tip
Metadata manbasi: jurnal OAI-PMH arxivi · Sindex toʻliq matnni saqlamaydi, manbaga havola beradi.