Марказий Осиё эндокринологик журнали 4-jild 4-son (2024)
RETROSPECTIVE ANALYSIS OF CLINICAL AND BIOCHEMICAL INDICATORS IN PATIENTS WITH METABOLIC SYNDROME WHO RECOVERED FROM COVID-19
Мирзаева Умида Захидовна, Насырова Хуршидахон Кудратуллаевна
Annotatsiya
Complications associated with coronavirus disease (COVID-19) are significantly prevalent among patients with comorbid conditions such as hypertension, obesity, and diabetes. Purpose of the Study: The aim of this study was to conduct a retrospective analysis of lipid profiles and carbohydrate metabolism in patients with a history of COVID-19 infection. Materials and Methods: A retrospective analysis was performed on the clinical data of 215 patients treated at the Republican Specialized Scientific-Practical Medical Center of Endocrinology, who were included in the database from January to August 2022. Of these, 127 patients had confirmed COVID-19 diagnoses via polymerase chain reaction (PCR) testing for SARS-CoV-2, while 88 patients had no history of COVID-19. Patients lacking data on body mass index (BMI), blood pressure, triglycerides (TG), total cholesterol (TC), glucose levels, insulin, and C-reactive protein (CRP) were excluded from the study. Results: Patients with metabolic syndrome (MS) who recovered from COVID-19 showed significantly more pronounced changes in hemodynamics (elevated systolic blood pressure), lipid metabolism (increased levels of TG, apolipoprotein B [ApoB], ApoB/ApoA1 ratio, and decreased levels of high-density lipoprotein cholesterol [HDL-C] and apolipoprotein A1 [ApoA1]), carbohydrate metabolism (elevated fasting glucose, insulin, and homeostatic model assessment of insulin resistance [HOMA-IR]), and inflammatory markers (elevated CRP) compared to patients with MS who had not contracted COVID-19 and those without MS who had recovered from COVID-19.
метаболический синдром, COVID-19, углеводный и липидный обмен, триглициридно-глюкозный индексMetabolic syndrome, COVID-19, carbohydrate metabolism, lipid metabolism, triglyceride-glucose indexmetabolik sindrom, COVID-19, uglevod va lipid almashinuvi, triglitserid-glyukoza indeksi
Metadata manbasi: jurnal OAI-PMH arxivi · Sindex toʻliq matnni saqlamaydi, manbaga havola beradi.