Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research 6-jild 5-son (2025)
ANALYSIS OF DIFFERENTIAL CHARACTERISTICS OF CLINICAL AND FUNCTIONAL CHANGES IN THE EARLY AND PRODROMAL STAGES OF PARKINSON'S DISEASE
Сафаров Комилжон Камолович, Хайдарова Дилдора Кодировна
Annotatsiya
Parkinson's disease (PD) is one of the most common neurodegenerative diseases characterized by the progressive loss of dopaminergic neurons in the brain's substantia nigra. Traditionally, the diagnosis of Parkinson's disease was based on the identification of classical motor symptoms - resting tremor, rigidity, bradykinesia, and postural instability. However, modern studies show that the pathological process in PD begins long before the manifestation of motor disorders, passing through the prodromal and early stages of the disease.
болезнь Паркинсона, продромальная стадия, ранняя стадия, немоторные симптомы, дифференциальная диагностика, дофаминергические нейроны, нейродегенерация, биомаркеры, нейровизуализацияParkinson's disease, prodromal stage, early stage, non-motor symptoms, differential diagnosis, dopaminergic neurons, neurodegeneration, biomarkers, neurovisualizationПаркинсон касаллиги, продромал босқич, эрта босқич, номотор аломатлар, дифференциал ташхис, дофаминергик нейронлар, нейродегенератсия, биомаркерлар, нейровизуализатсия
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