Товарлар кимёси ва халқ табобати 3-том 3-сан (2024) · 78-98-беттер

STEREOCHEMICAL CHARACTERISTICS AND BIOLOGICAL ACTIVITY OF ENANTIOMERIC (R)- AND (S)-4-METHYL-4-ETHYL-5-METHYLENETHIAZOLIDINES

Abdullaev, Tohir Kh., Askarov, Ibragim R., Isobaev, Muzafar D., Pulatov, Elmurod Kh.

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Аннотация

The paper presents some visions of the reaction of formation of sulfur-containing heterocycles. In the case of five-membered structures of the thiazolidine heterocycle type, a thione-thiol tautomeric equilibrium occurs, associated with the migration of a proton between the endocyclic nitrogen atom and the exocyclic sulfur atom. Data on thermodynamic characteristics and information on the stability of various configuration states make it possible to plan further reactions, depending on the selected conditions for their implementation. Biological tests of racemic and optically active “4-methyl-4-ethyl-5-methylenethiazolidin-2-thiones” showed that they have different degrees of bacteriostatic and bactericidal action in relation to various strains of bacteria.

ГетероциклытаутомерияПМР спектроскопияквантовохимический расчетоптически активный тиазолидинтионбиологическая активностьHeterocyclestautomerismPMR spectroscopyquantum chemical calculation

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Цитата алуу

APA 7 
Abdullaev, Tohir Kh., Askarov, Ibragim R., Isobaev, Muzafar D. & Pulatov, Elmurod Kh. (2024). STEREOCHEMICAL CHARACTERISTICS AND BIOLOGICAL ACTIVITY OF ENANTIOMERIC (R)- AND (S)-4-METHYL-4-ETHYL-5-METHYLENETHIAZOLIDINES. Товарлар кимёси ва халқ табобати, 3(3), 78-98.
GOST R 7.0.5 
Abdullaev, Tohir Kh., Askarov, Ibragim R., Isobaev, Muzafar D., Pulatov, Elmurod Kh. STEREOCHEMICAL CHARACTERISTICS AND BIOLOGICAL ACTIVITY OF ENANTIOMERIC (R)- AND (S)-4-METHYL-4-ETHYL-5-METHYLENETHIAZOLIDINES // Товарлар кимёси ва халқ табобати. 2024. Т. 3. № 3. С. 78-98.
BibTeX 
@article{kh.2024,
  author  = {Abdullaev, Tohir Kh. and Askarov, Ibragim R. and Isobaev, Muzafar D. and Pulatov, Elmurod Kh.},
  title   = {STEREOCHEMICAL CHARACTERISTICS AND BIOLOGICAL ACTIVITY OF ENANTIOMERIC (R)- AND (S)-4-METHYL-4-ETHYL-5-METHYLENETHIAZOLIDINES},
  journal = {Товарлар кимёси ва халқ табобати},
  year    = {2024},
  volume  = {3},
  number  = {3},
  pages   = {78-98}
}
RIS 
TY  - JOUR
AU  - Abdullaev, Tohir Kh.
AU  - Askarov, Ibragim R.
AU  - Isobaev, Muzafar D.
AU  - Pulatov, Elmurod Kh.
TI  - STEREOCHEMICAL CHARACTERISTICS AND BIOLOGICAL ACTIVITY OF ENANTIOMERIC (R)- AND (S)-4-METHYL-4-ETHYL-5-METHYLENETHIAZOLIDINES
JO  - Товарлар кимёси ва халқ табобати
PY  - 2024
VL  - 3
IS  - 3
SP  - 78
EP  - 98
ER  -