Товарлар кимёси ва халқ табобати 4-том 3-сан (2025) · 56-67-беттер

BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS

Isobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., Pulatov, Elmurod Kh.

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Аннотация

The article focuses on the synthesis of enyne triols and their stereochemical and conformational features. The preparation of Z- and E-isomers, their separation, and structural confirmation through spectroscopic methods are described. Analysis of NMR spectra and anisotropy calculations revealed conformational differences between the isomers. Pharmacological studies demonstrated that the synthesized enyne triols exhibit significant choleretic activity, with E-isomers being more active than Z-isomers. These findings highlight the potential of enyne triols as promising candidates for the development of new therapeutic agents.

organic chemistryenyne triolsZ/E-isomerismconformationNMR spectroscopyanisotropycholeretic activityорганическая химияенинтриолыZ/E-изомерия

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Цитата алуу

APA 7 
Isobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh. & Pulatov, Elmurod Kh. (2025). BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS. Товарлар кимёси ва халқ табобати, 4(3), 56-67.
GOST R 7.0.5 
Isobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., Pulatov, Elmurod Kh. BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS // Товарлар кимёси ва халқ табобати. 2025. Т. 4. № 3. С. 56-67.
BibTeX 
@article{j.2025,
  author  = {Isobaev, Muzafar J. and Fayzilov, Ikrom U. and Abdullaev, Tokhir Kh. and Pulatov, Elmurod Kh.},
  title   = {BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS},
  journal = {Товарлар кимёси ва халқ табобати},
  year    = {2025},
  volume  = {4},
  number  = {3},
  pages   = {56-67}
}
RIS 
TY  - JOUR
AU  - Isobaev, Muzafar J.
AU  - Fayzilov, Ikrom U.
AU  - Abdullaev, Tokhir Kh.
AU  - Pulatov, Elmurod Kh.
TI  - BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS
JO  - Товарлар кимёси ва халқ табобати
PY  - 2025
VL  - 4
IS  - 3
SP  - 56
EP  - 67
ER  -