Товарлар кимёси ва халқ табобати Volume 4 Issue 5 (2025) · pp. 132-143

TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS

Mamajonov, Zafar A., Ulug’bekova, Gulrukhan J., Mamatova, Iroda Yu.

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Abstract

Tumor-associated macrophages (TAMs) are one of the most abundant immune cell populations in the tumor microenvironment (TME). By interacting with tumor and stromal cells, TAMs promote angiogenesis, suppress adaptive immunity, and facilitate metastasis. Most TAMs resemble the M2-like phenotype, secreting immunosuppressive and pro-tumorigenic factors such as IL-10, TGF-β, and VEGF. Their functional reprogramming has been recognized as a promising target in cancer immunotherapy.

Tumor-associated macrophages (TAMs)M1/M2 polarizationangiogenesisimmunosuppressionmetastasisOпухоле-ассоциированные макрофаги (TAMs)поляризация M1/M2ангиогенезиммуносупрессияметастазы

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Cite

APA 7 
Mamajonov, Zafar A., Ulug’bekova, Gulrukhan J. & Mamatova, Iroda Yu. (2025). TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS. Товарлар кимёси ва халқ табобати, 4(5), 132-143.
GOST R 7.0.5 
Mamajonov, Zafar A., Ulug’bekova, Gulrukhan J., Mamatova, Iroda Yu. TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS // Товарлар кимёси ва халқ табобати. 2025. Т. 4. № 5. С. 132-143.
BibTeX 
@article{a.2025,
  author  = {Mamajonov, Zafar A. and Ulug’bekova, Gulrukhan J. and Mamatova, Iroda Yu.},
  title   = {TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS},
  journal = {Товарлар кимёси ва халқ табобати},
  year    = {2025},
  volume  = {4},
  number  = {5},
  pages   = {132-143}
}
RIS 
TY  - JOUR
AU  - Mamajonov, Zafar A.
AU  - Ulug’bekova, Gulrukhan J.
AU  - Mamatova, Iroda Yu.
TI  - TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS
JO  - Товарлар кимёси ва халқ табобати
PY  - 2025
VL  - 4
IS  - 5
SP  - 132
EP  - 143
ER  -