Klinik fanlar yilnomasi 2-том 4-нөмір (2025)

FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY

Ахмеджанова Саодат Фархадовна

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Аңдатпа

Functional hypothalamic amenorrhea (FHA) is a common cause of secondary amenorrhea in women of reproductive age, resulting from suppression of gonadotropin-releasing hormone (GnRH) secretion due to stress, energy deficiency, and psychosocial factors. This review summarizes current concepts of FHA pathogenesis, emphasizing the central role of kisspeptin and metabolic hormones in hypothalamic-pituitary-gonadal axis regulation. Clinical manifestations, diagnostic principles, and modern therapeutic strategies are discussed. Particular attention is paid to multidisciplinary approaches aimed at restoring energy balance, reducing stress, and implementing cognitive-behavioral therapy. Emerging treatments, including kisspeptin receptor agonists and leptin-based interventions, show promise for restoring ovulatory function and reproductive health.

functional hypothalamic amenorrhea, kisspeptin, GnRH, stress, energy deficiency, hypoestrogenism, fertilityфункциональная гипоталамическая аменорея, kisspeptin, GnRH, стресс, энергетический дефицит, гипоэстрогения, фертильностьfunktsional gipotalamik amenoreya, kisspeptin, GnRH, stress, energiya tanqisligi, gipooestrogeniya, fertilitet

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APA 7
Ахмеджанова Саодат Фархадовна (2025). FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY. Klinik fanlar yilnomasi, 2(4).
GOST R 7.0.5
Ахмеджанова Саодат Фархадовна FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY // Klinik fanlar yilnomasi. 2025. Т. 2. № 4.
BibTeX
@article{фархадовна2025,
  author  = {Ахмеджанова Саодат Фархадовна},
  title   = {FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY},
  journal = {Klinik fanlar yilnomasi},
  year    = {2025},
  volume  = {2},
  number  = {4}
}
RIS
TY  - JOUR
AU  - Ахмеджанова Саодат Фархадовна
TI  - FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY
JO  - Klinik fanlar yilnomasi
PY  - 2025
VL  - 2
IS  - 4
ER  -