Klinik fanlar yilnomasi 2-том 4-нөмір (2025)
BIOACTIVITY AND REMINERALIZATION POTENTIAL OF PARTICLE-SIZE-ENGINEERED GLASS IONOMER CEMENTS
Туйгунов Нозимжон Нематжон угли, Худанов Бахтинур Ойбутаевич
Аңдатпа
Contemporary restorative dentistry increasingly demands materials that are not merely inert fillers but active contributors to the oral environment. Conventional glass ionomer cements (GICs), while valued for chemical adhesion and fluoride release, are limited by modest mechanical strength and incomplete understanding of their bioactive potential. This study investigates how modification of filler particle size—at submicron, nano, and hybrid scales—affects ion release dynamics, pH evolution, and remineralization capacity of GICs. Three formulations, derived from Fuji IX GP Extra, were compared using ion-selective analysis and enamel microhardness recovery assays over 28 days. The hybrid formulation exhibited a sustained fluoride and calcium release pattern, faster pH neutralization, and superior enamel hardness recovery relative to the nano and submicron forms. These results demonstrate that particle-size engineering can effectively modulate the physicochemical interactions of GICs with the oral environment, enhancing their therapeutic potential for minimally invasive pediatric dentistry.
glass ionomer cement, particle size, fluoride release, pH, remineralization, hybrid GIC, enamel microhardness.стеклоиономерный цемент, размер частиц, выделение фторидов, pH, реминерализация, гибридный СИЦ, микротвёрдость эмали.stekloionomer tsement, zarralar o‘lchami, ftorid ajralishi, pH, remineralizatsiya, gibrid SITs, emal mikroqattiqligi.
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