Klinik fanlar yilnomasi Volume 3 Issue 2 (2026)

CLINICAL AND BIOCHEMICAL CHARACTERISTICS OF BLOOD PARAMETERS IN PREGNANT WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE

Мирзаева Г.П

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Abstract

Objective: To evaluate biochemical and acid-base blood parameters in pregnant women with preeclampsia complicated by chronic kidney disease (CKD), in order to determine the severity of multiple organ dysfunction and optimize individualized treatment strategies. Methods: A total of 93 pregnant women with moderate to severe preeclampsia were examined: 41 with CKD (main group) and 52 without CKD (comparison group). Blood biochemistry, protein spectrum, albumin functional activity, acid-base balance, and blood gas composition were evaluated. Results: Women with CKD showed pronounced lipid metabolism disorders, elevated creatinine, urea, cholesterol, and LDH levels. Total protein and albumin decreased, γ-globulins increased, and the albumin-globulin ratio was disrupted. Functional activity of albumin decreased, and the albumin toxicity index increased. Blood gas analysis revealed metabolic acidosis on a respiratory alkalosis background, reduced oxygen transport, and severe hypoxia.

chronic kidney disease, preeclampsia, pregnancy, preeclampsia, blood biochemistryхроническая болезнь почек, преэклампсия, беременность, преэклампсия, биохимические показатели кровиhomiladorlik, preeklampsiya, surunkali buyrak kasalligi, qonning bioximik ko‘rsatkichlari

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Cite

APA 7 
Мирзаева Г.П (2026). CLINICAL AND BIOCHEMICAL CHARACTERISTICS OF BLOOD PARAMETERS IN PREGNANT WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE. Klinik fanlar yilnomasi, 3(2).
GOST R 7.0.5 
Мирзаева Г.П CLINICAL AND BIOCHEMICAL CHARACTERISTICS OF BLOOD PARAMETERS IN PREGNANT WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE // Klinik fanlar yilnomasi. 2026. Т. 3. № 2.
BibTeX 
@article{г.п2026,
  author  = {Мирзаева Г.П},
  title   = {CLINICAL AND BIOCHEMICAL CHARACTERISTICS OF BLOOD PARAMETERS IN PREGNANT WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE},
  journal = {Klinik fanlar yilnomasi},
  year    = {2026},
  volume  = {3},
  number  = {2}
}
RIS 
TY  - JOUR
AU  - Мирзаева Г.П
TI  - CLINICAL AND BIOCHEMICAL CHARACTERISTICS OF BLOOD PARAMETERS IN PREGNANT WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE
JO  - Klinik fanlar yilnomasi
PY  - 2026
VL  - 3
IS  - 2
ER  -