Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) 5-jild 1-son (2024)
HERPETIC STOMATITIS IN PREGNANT WOMEN AS AN ETIOPATHOGENETIC FACTOR IN THE DEVELOPMENT OF ENDOTHELIAL DYSFUNCTION
Юлдашева Насиба Алишеровна, Усманова Шоира Равшанбековна, Комилова Адиба Закиржоновна
Annotatsiya
To evaluate some aspects of the development of herpetic stomatitis in pregnant women, to study the features of the functional state of endothelial cells, the content of ceruloplasmin and uric acid in the blood. 40 pregnant women in the second trimester with herpetic stomatitis were examined. The level of IL-10 in saliva, the content of uric acid in the blood, ceruloplasmin and markers of endothelial dysfunction were studied. An increase in the level of uric acid, ceruloplasmin was revealed against the background of a decrease in IL-10. Against the background of endothelial damage, activation of the plasma link of the hemostasis system was noted with the predominant prevalence of the plasmin system at the site of the focus of viral damage, which, if the destructive processes occurring at the site of the focus of viral infection are disrupted, may be accompanied by hemorrhage.
герпетический стоматит, церулоплазмин, маркеры, дисфункции эндотелияherpetic stomatitis, ceruloplasmin, markers, endothelial dysfunctionHerpetik stomatit, seruloplazmin, markerlar, endotelial disfunktsiyalar
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