Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) 7-jild 1-son (2026)
THE ROLE OF IRON AND B-GROUP VITAMIN DEFICIENCY IN THE DEVELOPMENT OF ANGULAR CHEILITIS IN PREGNANT WOMEN
Тахирова Камола Абраровна, Мирзаходжаева Нигина Фирдавсовна
Annotatsiya
Angular cheilitis is a common inflammatory disease of the oral mucosa often associated with systemic deficiency conditions. Pregnancy is accompanied by an increased demand for iron and B-group vitamins, the deficiency of which may contribute to inflammatory lesions in the corners of the mouth. The aim of this study was to investigate the role of iron and B-group vitamin deficiency in the development of angular cheilitis in pregnant women. The study included 40 pregnant patients divided into a main group (n=20) with angular cheilitis and a control group (n=20) without oral mucosal lesions. Clinical examination, complete blood count, serum ferritin, vitamin B₆ and vitamin B₁₂ levels were assessed.The results demonstrated a significant decrease in ferritin, vitamin B₆ and vitamin B₁₂ levels in pregnant women with angular cheilitis compared to the control group (p<0.05). These deficiency states were correlated with the severity of clinical manifestations. The findings confirm the important role of iron and B-group vitamin deficiency in the pathogenesis of angular cheilitis in pregnant women and highlight the necessity of comprehensive laboratory evaluation in this patient population.
ангулярный хейлит, беременность, дефицит железа, ферритин, витамин B₆, витамин B₁₂.angular cheilitis, pregnancy, iron deficiency, ferritin, vitamin B6, vitamin B12.angulyar xeylit, homiladorlik, temir yetishmovchiligi, ferritin, B₆ vitamini, B₁₂ vitamini.
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