Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali 2-том 2-сан (2021)
MECHANISMS OF FORMATION OF HEART DYSFUNCTION AND THE APPLICATION OF SAKUBUTRI/VALSARTAN IN DIABETES MELLITUS
Ташкенбаева Наргиза Фархадовна, Тригулова Раиса Хусаиновна, Халикова Азиза Ойбековна, Мухтарова Шахноза Шокиржоновна
Аннотация
The incidence of diabetes mellitus (DM) in patients with heart failure (HF) is about 40%, regardless of the level of ejection fraction (EF) impairment. But, in addition, diabetes is considered a strong independent risk factor for the progression of heart failure with both preserved and reduced EF and is usually associated with a poor prognosis. The ability of neprilisin inhibitors to increase levels of biologically active natriuretic peptides has made them a potential therapeutic approach in the treatment of HF. The use of sacubitril/valsartan in patients with heart failure with diabetes continues to be studied.
сердечная недостаточность, сахарный диабет, фракция выброса, сакубитрил/валсартанheart failure, diabetes mellitus, ejection fraction, sacubitril/valsartanyurak yetishmovchiligi, qandli diabet, yurakning otish fraktsiyasi, sakubitril/valsartan
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