Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali Volume 4 Issue 3 (2023)
MOLECULAR-GENETIC ASPECTS OF BRONCHIAL ASTHMA FORMATION AND THE IMPORTANCE OF β2-ADRENORECEPTOR GENE POLYMORPHISMS
Турдибеков Хусан Ибрагимович, Ким Антонина Амуровна, Пардаева Угилой Джамаловна, Куйлиев Каландар Уринович
Abstract
The study of the genetic basis of bronchial asthma susceptibility is reviewed in the literature. The molecular-genetic processes of bronchial asthma development are explained in detail. Analyzed are the findings of investigations on the relationship between the phenotypic symptoms of the illness and the polymorphism of the β2-adrenoceptor gene in various groups. The effects of polymorphic variations of the β2-adrenoceptor gene on the onset of asthma and the efficacy of this disease's therapy are discussed in this article. provided.
бронхиальная астма, ген β2-адренорецептора, полиморфный вариант, гены-кандидаты, ассоциацияbronchial asthma, β2-adrenoceptor gene, polymorphic variant, candidate genes, association.bronxialnaya astma, β2-adrenoreseptor geni, polimorf variant, gen-nomzodlar, assosiasiya.
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