Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali Volume 6 Issue 2 (2025)
CLINICAL FEATURES OF METABOLIC DISORDERS IN WOMEN WITH CARDIOVASCULAR PATHOLOGIES
Tuychieva Sabohat Kurakbayevna, Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна
Abstract
Cardiovascular diseases (CVD) remain one of the leading causes of mortality and disability among women over 40 years old. In recent decades, there has been an increase in comorbid conditions, among which metabolic syndrome (MS) plays a key role in the development and progression of coronary heart disease (CHD). Objective of the study: To investigate the characteristics of metabolic disorders in women with coronary heart disease and their impact on the progression of cardiovascular pathology. Materials and methods: 142 women over 40 years of age were examined at the Samarkand branch of the Republican Specialized Medical Scientific and Practical Center of Cardiology. The participants were divided into two groups: Group 1: 58 women (40.8%) with CHD and metabolic syndrome. Group 2 (comparison group): 54 women (38.0%) with CHD without signs of metabolic syndrome. Results: Analysis of the obtained data revealed that carbohydrate and lipid metabolism disorders were more pronounced in women with CHD and MS compared to patients with CHD without MS. In the group of patients with MS, elevated levels of fasting glucose, insulin, and HOMA-IR index were detected, indicating marked insulin resistance.
метаболический синдром, артериальная гипертензия, липидный профиль, индекс массы тела, ожирениеmetabolic syndrome, arterial hypertension, lipid profile, body mass index, obesitymetabolik sindrom, arterial gipertenziya, lipid profili, tana vazni indeksi, semizlik
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