Саноатда рақамли технологиялар Volume 4 Issue 2 (2026) · pp. 186-192

DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS

Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna

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Abstract

This study presents a technology for producing highly purified sodium carboxymethyl cellulose (Na-CMC) from cellulose extracted from locally available mashar stems for medical applications, particularly in the manufacture of medical gypsum. Technical Na-CMC was purified by ethanol extraction using a 53% aqueous ethanol solution, and the influence of extraction time on the purity and quality of the final product was systematically investigated. The optimum extraction time was found to be 40 min, resulting in a maximum main substance content of 99%. The physicochemical properties of the purified Na-CMC, including degree of substitution, dynamic viscosity, water solubility, and pH, were determined and compared with the requirements of relevant technical standards. X-ray diffraction (XRD) analysis confirmed the successful structural transformation of cellulose into Na-CMC through a reduction in crystallinity after carboxymethylation. The results demonstrate that mashar stem cellulose is a promising renewable local raw material for the production of pharmaceutical-grade Na-CMC with properties suitable for medical gypsum and other biomedical applications.

Na-CMCmashar stemcelluloseethanol extractionmedical gypsumX-ray diffractionphysicochemical propertiesNa-CMCстебель машарацеллюлоза

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Cite

APA 7 
Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich & Jurayeva, Huriyat Zoirovna (2026). DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS. Саноатда рақамли технологиялар, 4(2), 186-192.
GOST R 7.0.5 
Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS // Саноатда рақамли технологиялар. 2026. Т. 4. № 2. С. 186-192.
BibTeX 
@article{xolmurodovich2026,
  author  = {Sattorov, Laziz Xolmurodovich and Kurbanov, Abdiraxim Axmedovich and Rahmatov, Xudoyor Boboniyozovich and Jurayeva, Huriyat Zoirovna and Сатторов, Лазиз Холмуродович and Курбанов, Абдирахим Ахмедович and Рахматов, Худоёр Бобониёзович and Джураева, Хурият Зоировна and Sattorov, Laziz Xolmurodovich and Kurbanov, Abdiraxim Axmedovich and Rahmatov, Xudoyor Boboniyozovich and Jurayeva, Huriyat Zoirovna},
  title   = {DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS},
  journal = {Саноатда рақамли технологиялар},
  year    = {2026},
  volume  = {4},
  number  = {2},
  pages   = {186-192}
}
RIS 
TY  - JOUR
AU  - Sattorov, Laziz Xolmurodovich
AU  - Kurbanov, Abdiraxim Axmedovich
AU  - Rahmatov, Xudoyor Boboniyozovich
AU  - Jurayeva, Huriyat Zoirovna
AU  - Сатторов, Лазиз Холмуродович
AU  - Курбанов, Абдирахим Ахмедович
AU  - Рахматов, Худоёр Бобониёзович
AU  - Джураева, Хурият Зоировна
AU  - Sattorov, Laziz Xolmurodovich
AU  - Kurbanov, Abdiraxim Axmedovich
AU  - Rahmatov, Xudoyor Boboniyozovich
AU  - Jurayeva, Huriyat Zoirovna
TI  - DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS
JO  - Саноатда рақамли технологиялар
PY  - 2026
VL  - 4
IS  - 2
SP  - 186
EP  - 192
ER  -