Марказий Осиё эндокринологик журнали 3-jild 1-son (2023)
THE PREVALENCE OF CARBOHYDRATE METABOLISM DISORDERS IN PATIENTS AFTER CORONAVIRUS INFECTION
Рахимова Г.Н., Парпиева Н.Н., Хусанов А.М., Тилляшайхова И.М., Нурматов А.Х.
Annotatsiya
Background. The current COVID-19 pandemic shows that there is a two-way interaction between diabetes mellitus (DM) and the 2019 coronavirus disease, COVID-19. On the one hand, people with diabetes are at higher risk of death due to intensive COVID-19 treatment and intensive care, and COVID-19 related, compared to people without diabetes. On the other hand, clinical data and current data prove that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to metabolic dysregulation and impaired glucose homeostasis. Objective. To analyze the incidence of new cases of diabetes in patients with Covid-19, to compare clinical outcomes and comorbidities in patients with and without diabetes Methods. The observational monocenter longitudinal controlled study involved 108 people who were divided into groups: patients with newly diagnosed diabetes, with type 1 and 2 diabetes mellitus, patients without carbohydrate metabolism disorders. The mean age of the patients was ±51.3 years. To verify carbohydrate metabolism disorders, all patients underwent fasting blood glucose testing. Anamnesis, clinical examination, measurement of blood pressure, heart rate, and BMI parameters were also carried out to assess concomitant diseases. Results. Of 267 patients, carbohydrate metabolism disorders were detected in 44.9% of patients, while 23.9% had newly diagnosed diabetes, 18.7% had type 2 diabetes mellitus, and 2.2% had type 1 diabetes. After analyzing the data, it was found that patients with impaired carbohydrate metabolism have a worse prognosis and outcomes of the disease. Conclusion. COVID-19 causes dysregulation of glucose homeostasis, leading to the development of hyperglycemia and diabetes mellitus. Patients with impaired carbohydrate metabolism have more severe outcomes of COVID-19. Indicators such as the severity of the condition, hospitalization in the intensive care unit are highest in patients with diabetes mellitus and concomitant diseases.
COVID-19, сахарный диабет 1и 2 типа, коронавирусCOVID-19, diabetes mellitus type 1 and type 2, coronavirusCOVID-19, 1 тур қандли диабет, 2 тур қандли диабет, коронавирус
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