Марказий Осиё эндокринологик журнали Volume 5 Issue 2 (2025)
DYNAMIC ANALYSIS OF THE RESULTS OF RADIATION THERAPY FOR PRIMARY BRAIN TUMORS
Шагазатова Барно Хабибуллаевна, Артикова Дилфуза Махаматовна, Алимов Жамшид Махмуджонович
Abstract
Relevance. The number of oncological diseases is growing from year to year. This is due to the widespread use of computer-based visualized research methods in the modern world. Brain tumors occupy a special place among oncopathology. The treatment of brain tumors is an urgent problem of modern neuro-oncology, since the survival rate of patients remained low until recently, and the disease itself led to an increase in cases of disability and a decrease in quality of life. Objective: to conduct an analytical structured analysis of the data of patients who received radiation for primary brain tumors. Materials and methods: 333 patients underwent a retrospective and prospective analysis of their medical records from 2018 to 2024 with an assessment of the results of radiation therapy. The patients received a single focal dose (SFD) of an average of 2.09 ± 0.05 Gr once a day for 5 days and a total focal dose (TFD) of 52.56±0.57 Gr. Results: Out of 333 patients who received radiation therapy, 178 patients (53.4%) were alive. The number of deceased patients was 155, which corresponds to 46.6% of cases. Of these, 93 are men and 62 are women. 53 people (34.1%) died in the first year after radiation therapy. Conclusions: antitumor radiation therapy was performed in 70.9% of cases by the IMRI method; brain tumors accounted for 90.7% and their main localization was in the frontal lobe (24.5%); after radiation therapy, the number of deaths was higher among men.
головной мозг, лучевая терапия, разовая очаговая доза, суммарная очаговая доза, IMRT, 3D-CRT, VMAT, SRS, ДГТbrain, radiation therapy, single focal dose, total focal dose, IMRI, 3D-CRT, VMAT, SRS, DGTbosh miya, nur terapiyasi, bir martali o‘choq dozasi, umumiy o‘choq dozasi, intensi IMRT, 3D-CRT, VMAT, SRS, DGT
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