O‘zbekiston кardiologiyasi Volume 1 Issue 1 (2024) · pp. 43-50

The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research

Юсупалиева, Д, Низамов, У, Алиева, Р, Ахмедова, Ш, Шек, А, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista, Shek, Aleksandr, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista, Shek, Aleksandr

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Abstract

Background. Atherosclerosis is a leading cause of cardiovascular mortality worldwide, significantly impacting public health. microRNA, as key regulators of gene expression, play a crucial role in the pathogenesis of atherosclerosis, offering novel avenues for diagnostics and therapeutics. Materials and methods. A review of contemporary literature was conducted to explore the link between non-coding molecules and atherosclerosis. Data from clinical studies identifying microRNA as potential biomarkers and therapeutic targets were included. Results.The findings demonstrate that microRNA influence critical stages of atherosclerosis pathogenesis, such as inflammation, apoptosis, and lipid metabolism. Their use as diagnostic biomarkers enhances the early detection of atherosclerosis, while their therapeutic potential presents new opportunities for treatment. Conclusion. MicroRNA represent a promising tool for managing cardiovascular diseases. Further research is necessary to develop effective diagnostic and therapeutic strategies.

atherosclerosisbiomarkersinflammationmicroRNAnon-coding moleculespathogenesistherapeutic targetsaтеросклерозбиомаркерывоспаление

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Cite

APA 7 
Юсупалиева, Д, Низамов, У, Алиева, Р, Ахмедова, Ш, Шек, А, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista, Shek, Aleksandr, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista & Shek, Aleksandr (2024). The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research. O‘zbekiston кardiologiyasi, 1(1), 43-50.
GOST R 7.0.5 
Юсупалиева, Д, Низамов, У, Алиева, Р, Ахмедова, Ш, Шек, А, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista, Shek, Aleksandr, Yusupalieva, Dilnora, Nizamov, Ulugbek, Alieva, Rano, Akhmedova, Shokhista, Shek, Aleksandr The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research // O‘zbekiston кardiologiyasi. 2024. Т. 1. № 1. С. 43-50.
BibTeX 
@article{д2024,
  author  = {Юсупалиева, Д and Низамов, У and Алиева, Р and Ахмедова, Ш and Шек, А and Yusupalieva, Dilnora and Nizamov, Ulugbek and Alieva, Rano and Akhmedova, Shokhista and Shek, Aleksandr and Yusupalieva, Dilnora and Nizamov, Ulugbek and Alieva, Rano and Akhmedova, Shokhista and Shek, Aleksandr},
  title   = {The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research},
  journal = {O‘zbekiston кardiologiyasi},
  year    = {2024},
  volume  = {1},
  number  = {1},
  pages   = {43-50}
}
RIS 
TY  - JOUR
AU  - Юсупалиева, Д
AU  - Низамов, У
AU  - Алиева, Р
AU  - Ахмедова, Ш
AU  - Шек, А
AU  - Yusupalieva, Dilnora
AU  - Nizamov, Ulugbek
AU  - Alieva, Rano
AU  - Akhmedova, Shokhista
AU  - Shek, Aleksandr
AU  - Yusupalieva, Dilnora
AU  - Nizamov, Ulugbek
AU  - Alieva, Rano
AU  - Akhmedova, Shokhista
AU  - Shek, Aleksandr
TI  - The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research
JO  - O‘zbekiston кardiologiyasi
PY  - 2024
VL  - 1
IS  - 1
SP  - 43
EP  - 50
ER  -