O‘zbekiston кardiologiyasi Volume 2 Issue 1 (2025) · pp. 39-45
Gender-specific features of dilated cardiomyopathy in the uzbek population
Абдуллаев, Т, Цой, И, Гуломов, Х, Мирзарахимова, С, Худойберганов, О, Рахматов, М, Abdullayev, Timur, Soy, Igor, Gulomov, Xumoyun, Mirzaraximova, Saodat, Xudoyberganov, Otabek, Raxmatov, Maxmud, Abdullayev, Timur, Soy, Igor, Gulomov, Khumoyun, Mirzarakhimova, Saodat, Khudoyberganov, Otabek, Rakhmatov, Makhmud
Abstract
Dilated cardiomyopathy (DCM) is one of the most common non-ischemic myocardial disease characterized by systolic dysfunction and cardiac chamber dilation. Gender-specific features of DCM progression and prognosis remain understudied. Aim. To evaluate gender-specific characteristics of medical history, clinical presentation, and functional parameters in patients with DCM in the Uzbek population. Materials and methods. A retrospective analysis included 269 DCM patients (180 men, 89 women) treated at the Republican Specialized Scientific-Practical Medical Center of Cardiology from 2010 to 2017. Data on age at diagnosis, disease duration, hospitalizations, NYHA class, hemodynamics, and six-minute walking test were assessed. Statistical analysis involved t-test and χ2 test (p < 0.05). Results. Women were younger at diagnosis (33.7 vs. 41.3 years; p < 0.001), had shorter disease duration (p = 0.041), and were hospitalized more frequently (75% vs. 65%; p = 0.041). No significant differences were found in NYHA class, blood pressure, or respiratory parameters. Men demonstrated better physical endurance (p = 0.191). Conclusion. Significant gender differences were identified, underscoring the need for personalized management of DCM patients.
dilated cardiomyopathygender differencesretrospective analysisUzbek populationdilated kardiyomiyopatiyagenderga xos farqlarretrospektiv tahlilO‘zbek populyatsiyasiдилатационная кардиомиопатиягендерные различия
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