O‘zbekiston кardiologiyasi Volume 2 Issue 2 (2025) · pp. 99-109

An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions

Садуллоева, Мохинур, Закирова, Ф, Турсунова, М, Абдухакимов, А, Икрамова, С, Джураева, В, Sadulloeva, Mokhinur, Zakirova, Feruza, Tursunova, Malika, Abdukhakimov, Abror, Ikramova, Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova, Feruza, Tursunova, Malika, Abduxakimov, Abror, Ikramova, Saida, Juraeva, Vasilaxon

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Abstract

Aim. Hypertensive disorders complicate one in ten pregnancies, which necessitates the development of new standards for determining the risk of preeclampsia and heart failure in pregnant women. To determine early clinical markers in pregnant women with gestational arterial hypertension (GAH) as sensitive diagnostic criteria for the development of hypertensive complications. Materials and methods. The study included 91 pregnant women of the 2nd-3rd trimesters, divided into groups: healthy pregnant women (n=44) and with GAH (n=47) according to the ESC Guidelines 2018. Physical examination, blood pressure measurement, BMI calculation, detailed blood tests including lipidogram, coagulogram, determination of prolactin and NT-proBNP, echocardiography, vascular stress test to assess endothelial function were performed. Results. Pregnant women with GAH were found to have morphofunctional changes in the heart, early signs of endothelial dysfunction, lipid and carbohydrate metabolism disorders. Microalbuminuria demonstrated high diagnostic value for detecting early renal dysfunction. The prognostic significance of prolactin and NT-proBNP levels was established. Conclusion. Comprehensive early monitoring of clinical and biochemical parameters of pregnant women with GAG is necessary for timely detection of preeclampsia predictors. The results contribute to the improvement of diagnostic and preventive standards for the management of this cohort of patients.

Артериальная гипертензияпреэклампсиясердечная недостаточностьматеринская смертностьэндотелиальная дисфункцияпролактингестационная артериальная гипертензияarterial hypertensionpreeclampsiaheart failure

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Cite

APA 7 
Садуллоева, Мохинур, Закирова, Ф, Турсунова, М, Абдухакимов, А, Икрамова, С, Джураева, В, Sadulloeva, Mokhinur, Zakirova, Feruza, Tursunova, Malika, Abdukhakimov, Abror, Ikramova, Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova, Feruza, Tursunova, Malika, Abduxakimov, Abror, Ikramova, Saida & Juraeva, Vasilaxon (2025). An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions. O‘zbekiston кardiologiyasi, 2(2), 99-109.
GOST R 7.0.5 
Садуллоева, Мохинур, Закирова, Ф, Турсунова, М, Абдухакимов, А, Икрамова, С, Джураева, В, Sadulloeva, Mokhinur, Zakirova, Feruza, Tursunova, Malika, Abdukhakimov, Abror, Ikramova, Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova, Feruza, Tursunova, Malika, Abduxakimov, Abror, Ikramova, Saida, Juraeva, Vasilaxon An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions // O‘zbekiston кardiologiyasi. 2025. Т. 2. № 2. С. 99-109.
BibTeX 
@article{мохинур2025,
  author  = {Садуллоева, Мохинур and Закирова, Ф and Турсунова, М and Абдухакимов, А and Икрамова, С and Джураева, В and Sadulloeva, Mokhinur and Zakirova, Feruza and Tursunova, Malika and Abdukhakimov, Abror and Ikramova, Saida and Djuraeva, Vasilakhon and Sadulloeva, Moxinur and Zakirova, Feruza and Tursunova, Malika and Abduxakimov, Abror and Ikramova, Saida and Juraeva, Vasilaxon},
  title   = {An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions},
  journal = {O‘zbekiston кardiologiyasi},
  year    = {2025},
  volume  = {2},
  number  = {2},
  pages   = {99-109}
}
RIS 
TY  - JOUR
AU  - Садуллоева, Мохинур
AU  - Закирова, Ф
AU  - Турсунова, М
AU  - Абдухакимов, А
AU  - Икрамова, С
AU  - Джураева, В
AU  - Sadulloeva, Mokhinur
AU  - Zakirova, Feruza
AU  - Tursunova, Malika
AU  - Abdukhakimov, Abror
AU  - Ikramova, Saida
AU  - Djuraeva, Vasilakhon
AU  - Sadulloeva, Moxinur
AU  - Zakirova, Feruza
AU  - Tursunova, Malika
AU  - Abduxakimov, Abror
AU  - Ikramova, Saida
AU  - Juraeva, Vasilaxon
TI  - An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions
JO  - O‘zbekiston кardiologiyasi
PY  - 2025
VL  - 2
IS  - 2
SP  - 99
EP  - 109
ER  -