O‘zbekiston кardiologiyasi Том 2 № 4 (2025) · с. 399-406

Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature

Sokhibov, Dilshod, Trigulova, Raisa, Mirakhmedova, Nilufar, Сохибов, Дилшод, Тригулова, Р, Мирахмедова, Нилуфар, Soxibov, Dilshod, Trigulova, Raisa, Miraxmedova, Nilufar

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Аннотация

Aim. To systematically analyze current approaches to assessing and improving medication adherence in patients after acute myocardial infarction during outpatient follow-up, with a particular focus on factors influencing treatment adherence and the role of a multidisciplinary approach. Materials and Methods. A systematic review of the literature on medication adherence after acute myocardial infarction was conducted. Data from large international studies were analyzed, including a meta-analysis of 10 studies involving 106,002 patients, the 2023 American Heart Association scientific statement, the 2023 ESC and 2025 ACC/AHA guidelines, and current cardiac rehabilitation programs. Results. A meta-analysis showed that good adherence to drug therapy is associated with reduced all-cause mortality (odds ratio 0.56; 95% CI: 0.45-0.69), cardiovascular mortality (OR 0.66; 95% CI: 0.51-0.87), and hospitalization rates (OR 0.61; 95% CI: 0.45-0.82). Non-adherence to therapy occurs in 30% of patients after myocardial infarction. Shared decision making, structured cardiac rehabilitation programs, and the involvement of multidisciplinary teams significantly improve long-term treatment adherence. Conclusion. Adherence to drug therapy is a key factor in improving the prognosis of patients after acute myocardial infarction. A multidisciplinary approach, including shared decision making, patient education, pharmaceutical counseling, and the use of digital technologies, demonstrates the greatest effectiveness in improving adherence.

acute myocardial infarctionadherence to therapyoutpatient monitoringcardiac rehabilitationshared decision makingострый инфаркт миокардаприверженность терапииамбулаторное наблюдениекардиологическая реабилитациясовместное принятие решений

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APA 7 
Sokhibov, Dilshod, Trigulova, Raisa, Mirakhmedova, Nilufar, Сохибов, Дилшод, Тригулова, Р, Мирахмедова, Нилуфар, Soxibov, Dilshod, Trigulova, Raisa & Miraxmedova, Nilufar (2025). Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature. O‘zbekiston кardiologiyasi, 2(4), 399-406.
GOST R 7.0.5 
Sokhibov, Dilshod, Trigulova, Raisa, Mirakhmedova, Nilufar, Сохибов, Дилшод, Тригулова, Р, Мирахмедова, Нилуфар, Soxibov, Dilshod, Trigulova, Raisa, Miraxmedova, Nilufar Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature // O‘zbekiston кardiologiyasi. 2025. Т. 2. № 4. С. 399-406.
BibTeX 
@article{dilshod2025,
  author  = {Sokhibov, Dilshod and Trigulova, Raisa and Mirakhmedova, Nilufar and Сохибов, Дилшод and Тригулова, Р and Мирахмедова, Нилуфар and Soxibov, Dilshod and Trigulova, Raisa and Miraxmedova, Nilufar},
  title   = {Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature},
  journal = {O‘zbekiston кardiologiyasi},
  year    = {2025},
  volume  = {2},
  number  = {4},
  pages   = {399-406}
}
RIS 
TY  - JOUR
AU  - Sokhibov, Dilshod
AU  - Trigulova, Raisa
AU  - Mirakhmedova, Nilufar
AU  - Сохибов, Дилшод
AU  - Тригулова, Р
AU  - Мирахмедова, Нилуфар
AU  - Soxibov, Dilshod
AU  - Trigulova, Raisa
AU  - Miraxmedova, Nilufar
TI  - Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature
JO  - O‘zbekiston кardiologiyasi
PY  - 2025
VL  - 2
IS  - 4
SP  - 399
EP  - 406
ER  -