Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 6 Issue 1 (2021)
ESTIMATION OF THE EFFICIENCY OF ANTISSEAL COATING ON THE MODEL OF LUNG WOUND IN EXPERIMENT
Мухаммад Мукумбоевич Дусияров, Отабек Джураевич Эшонходжаев, Зайниддин Яхшибоевич Сайдуллаев, Гайрат Келдибаевич Ахмедов
Abstract
Postoperative adhesion formation is the most common complication in general surgical practice with a frequency of more than 90% after abdominal surgery and up to 70% after thoracic surgery (Aysan E. et al. 2020, Banka R. et al. 2018). The frequency of relaparotomy and retorakotomy, according to various literature data, is estimated at 63% -97% (Bhatnagar R. et al. 2016, De Wilde RL et al. 2016). Repeated surgical procedures are more time-consuming and technically difficult, which, in turn, creates a potential risk of damage to vital structures. The paper analyzes the results of experimental and morphological studies, substantiates the effectiveness of the prevention of adhesion formation by using a domestic anti-adhesion agent in the form of a powder from cellulose derivatives. The biological safety of the new anti-adhesive coating has been determined under experimental conditions. 32 white outbred rats were used as experimental animals.
абдоминальная хирургия, торокальная хирургия, брющная полость, грудная полость, операция, спайки, профилактикаabdominal surgery, torocal surgery, abdominal cavity, chest cavity, operation, adhesions, preventionабдоминал хирургия, торокал хирургия, қорин бўшлиғи, кўкрак қафаси бўшлиғи, операция, битишмалар, профилактика
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