Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 7 Issue 1 (2022)

EVALUATION OF THE COMPARATIVE ACTIVITY OF GOSSYPOL COTTON CELLULOSE DERIVATIVE AND DICLOFENAC SODIUM ON THE DEVELOPMENT OF CHRONIC AUTOIMMUNE INFLAMMATION

ХАКИМОВ Зиявиддин Зайнутдинович, ЮЛДАШЕВ Журабек Исажанович, РАХМАНОВ Алишер Худайбердиевич

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Abstract

Gossypol, a cotton cellulose derivative, like diclofenac sodium, inhibits the development of the inflammatory process  in adjuvant-induced arthritis model in male white rats. The data of hematological studies and the level of C-reactive protein in the blood indicate a high pharmacological activity of gossypol, a derivative of cotton cellulose, which does not significantly differ from diclofenac sodium. It is believed that the restoration of the level of anti-inflammatory cytokines against the background of a acute decrease in pro-inflammatory cytokines has a great importance in the mechanism of the antiphlogogenic action of cotton cellulose derivative gossypol.

адъювант индуцированный артрит, гематология, цитокины, целлюлоза, госсиполadjuvant induced arthritis, hematology, cytokines, tsellyuloza, gossipolадъювантли артрит,гематология, цитокинлар, целлюлоза, госсипол

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Cite

APA 7 
ХАКИМОВ Зиявиддин Зайнутдинович, ЮЛДАШЕВ Журабек Исажанович & РАХМАНОВ Алишер Худайбердиевич (2022). EVALUATION OF THE COMPARATIVE ACTIVITY OF GOSSYPOL COTTON CELLULOSE DERIVATIVE AND DICLOFENAC SODIUM ON THE DEVELOPMENT OF CHRONIC AUTOIMMUNE INFLAMMATION. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(1).
GOST R 7.0.5 
ХАКИМОВ Зиявиддин Зайнутдинович, ЮЛДАШЕВ Журабек Исажанович, РАХМАНОВ Алишер Худайбердиевич EVALUATION OF THE COMPARATIVE ACTIVITY OF GOSSYPOL COTTON CELLULOSE DERIVATIVE AND DICLOFENAC SODIUM ON THE DEVELOPMENT OF CHRONIC AUTOIMMUNE INFLAMMATION // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. 2022. Т. 7. № 1.
BibTeX 
@article{зайнутдинович2022,
  author  = {ХАКИМОВ Зиявиддин Зайнутдинович and ЮЛДАШЕВ Журабек Исажанович and РАХМАНОВ Алишер Худайбердиевич},
  title   = {EVALUATION OF THE COMPARATIVE ACTIVITY OF GOSSYPOL COTTON CELLULOSE DERIVATIVE AND DICLOFENAC SODIUM ON THE DEVELOPMENT OF CHRONIC AUTOIMMUNE INFLAMMATION},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year    = {2022},
  volume  = {7},
  number  = {1}
}
RIS 
TY  - JOUR
AU  - ХАКИМОВ Зиявиддин Зайнутдинович
AU  - ЮЛДАШЕВ Журабек Исажанович
AU  - РАХМАНОВ Алишер Худайбердиевич
TI  - EVALUATION OF THE COMPARATIVE ACTIVITY OF GOSSYPOL COTTON CELLULOSE DERIVATIVE AND DICLOFENAC SODIUM ON THE DEVELOPMENT OF CHRONIC AUTOIMMUNE INFLAMMATION
JO  - Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
PY  - 2022
VL  - 7
IS  - 1
ER  -