Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 7-tom 6-san (2022)

THE SIGNIFICANCE OF THE G681A ALLELIC POLYMORPHISM OF THE CYP2C19 GENE IN THE GENESIS OF MALE FERTILITY DISORDERS

ИРГАШЕВ Дильмурад Саатович, ГАСАНОВА Шахина Сардаровна, БОБОЕВ Кодиржон Тухтабаевич

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Annotaciya

The role of the G681A polymorphism of the CYP2C19 gene in the formation of male infertility was analyzed. The study was conducted on a sample of 140 patients with various clinical forms of male infertility and 155 conditionally healthy fertile men. Despite the involvement of this locus in the regulation of the synthesis of sex hormones, especially androgens, the carriage of an unfavorable variant of this gene does not have an independent phenotypic effect on male fertility disorders, which allows us to conclude that this gene does not play an independent role in the genesis of male fertility disorders.

мужское бесплодие, полиморфизм G681A гена CYP2C19, аллель, генотип.male infertility, G681A polymorphism of the CYP2C19 gene, allele, genotypeerkaklar bepushtligi, CYP2C19 genining G681A polimorfizmi, allel, genotip

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APA 7 
ИРГАШЕВ Дильмурад Саатович, ГАСАНОВА Шахина Сардаровна & БОБОЕВ Кодиржон Тухтабаевич (2022). THE SIGNIFICANCE OF THE G681A ALLELIC POLYMORPHISM OF THE CYP2C19 GENE IN THE GENESIS OF MALE FERTILITY DISORDERS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(6).
GOST R 7.0.5 
ИРГАШЕВ Дильмурад Саатович, ГАСАНОВА Шахина Сардаровна, БОБОЕВ Кодиржон Тухтабаевич THE SIGNIFICANCE OF THE G681A ALLELIC POLYMORPHISM OF THE CYP2C19 GENE IN THE GENESIS OF MALE FERTILITY DISORDERS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. 2022. Т. 7. № 6.
BibTeX 
@article{саатович2022,
  author  = {ИРГАШЕВ Дильмурад Саатович and ГАСАНОВА Шахина Сардаровна and БОБОЕВ Кодиржон Тухтабаевич},
  title   = {THE SIGNIFICANCE OF THE G681A ALLELIC POLYMORPHISM OF THE CYP2C19 GENE IN THE GENESIS OF MALE FERTILITY DISORDERS},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year    = {2022},
  volume  = {7},
  number  = {6}
}
RIS 
TY  - JOUR
AU  - ИРГАШЕВ Дильмурад Саатович
AU  - ГАСАНОВА Шахина Сардаровна
AU  - БОБОЕВ Кодиржон Тухтабаевич
TI  - THE SIGNIFICANCE OF THE G681A ALLELIC POLYMORPHISM OF THE CYP2C19 GENE IN THE GENESIS OF MALE FERTILITY DISORDERS
JO  - Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
PY  - 2022
VL  - 7
IS  - 6
ER  -