Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 7-том 6-сан (2022)
SIGNIFICANCE OF IMMUNOLOGICAL BIOMARKERS IN THE DEVELOPMENT OF NONSPECIFIC INTERSTITINAL PNEUMONIA
МАХМАТМУРАДОВА Наргиза Негматуллаевна
Аннотация
The article is devoted to the significance of the content of neutrophil elastase and interleukins (IL-1b, IL-17A) in the blood of patients with nonspecific interstitial pneumonia. The regulation of the inflammatory response in nonspecific interstitial pneumonia depends on a complex interaction between immune cells and inflammatory-specific and anti-inflammatory cytokines. Enzymes of proteolysis (neutrophil elastase) can serve as a diagnostic marker that determines the severity of nonspecific interstitial pneumonia. In nonspecific interstitial pneumonia, disturbances are noted in the form of a change in the concentration of interleukins - IL-1β, IL-17A in the blood serum of immunocompetent cells of the peripheral blood flow. Changes in the concentration of cytokinins and neutrophil elastase indicate a correlation with the severity of the disease.
неспецифическая интерстициальная пневмония, сыворотка крови, нейтрофильная эластаза, интерлейкиныnonspecific interstitial pneumonia, blood serum, neutrophil elastase, interleukinsnospetsifik interstitsinal pnevmoniya, qon zardobi, neytrofil elastaza, interleykinlar
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