Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Том 7 № 6 (2022)
EFFECT OF ANEMIA AND HAPTOGLOBIN PHENOTYPE ON RHEUMATOID ARTHRITIS
РИЗАЕВ Жасур Алимджанович, ШОДИКУЛОВА Гуландом Зикрияевна, ПУЛАТОВ Улугбек Сунатович
Аннотация
Objective: determination of the level of anemia and clinical and laboratory parameters in patients with rheumatoid arthritis, depending on the haptoglobin system of different phenotypes. Methods: The study was conducted on 214 patients diagnosed with rheumatoid arthritis who were treated in the Samarkand city medical association during 2018-2021. The study used general clinical, medico-social, hematological, biochemical, immunological, instrumental and statistical research methods. Results: All patients with RA according to hematological parameters were divided into 2 groups: 50 (23.4%) patients without anemia, who made up our control group; the remaining 164 (76.6%) patients were diagnosed with anemia by hematological parameters, these patients constituted the main group. The type and degree of anemia in RA patients was determined in accordance with the classification recommended by WHO. ACD was observed in 94 (57.3%) patients, IDA in 65 (39.6%) patients, and 5 patients (3.1%) had both ACD and IDA. Conclusions. 76.6% of all RA patients participating in the study were diagnosed with anemia of various forms and degrees, which are characterized by a relationship between the duration, activity and radiographic manifestations of the disease
гаптоглобиновый фенотип, ревматоидный артрит (РА), анемия, ферритин, анемия хронических заболеваний, железодефицитная анемияhaptoglobin phenotype, rheumatoid arthritis (RA), anemia, ferritin, anemia of chronic disease, iron deficiency anemiagaptoglobinga ko’ra fenotip, revmatoid artrit (RA), anemiya, kam qonlik, ferritin, surunkali kasalliklar anemiyasi, temir tanqisligi anemiyasi
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