Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Том 8 № 1 (2023)
RELATIONSHIP OF THE LEVEL OF NEUTROPHILS IN PERIODONTITIS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASES. (Literature review)
РИЗАЕВ Жасур Алимжанович, НУРМАТОВ Ортик Саттор угли, ИСМОИЛОВ Ражаббой Махмаюсуф угли
Аннотация
The main cause of cardiovascular disease is atherosclerosis. Atherosclerosis is a chronic inflammatory vascular disease that results in the deposition of lipid plaques in the arterial wall. The accumulation and progression of these plaques can reduce blood flow, leading to ischemia of all organs and tissues, as well as contribute to the formation of blood clots. Major heart diseases associated with atherosclerosis include myocardial infarction, acute coronary syndrome, heart failure, arrhythmias, and cardiomyopathy. Worldwide, cardiovascular disease is the number one cause of death and is the leading cause of death. Because atherosclerosis is a chronic inflammatory disease, researchers sought to understand whether other inflammatory conditions could contribute to atherosclerosis and worsen the course of the disease. One of the little-studied inflammatory conditions was periodontitis. Periodontal disease (including gingivitis) resulting from various types of plaque is estimated by some studies to affect 47.2% of adults in the United States aged 30 years and older. This figure increases to 70% after age 65. In addition to oral care habits, factors that contribute to periodontal disease include socioeconomic status, gender, and smoking. Periodontitis ranks sixth in the world among all diseases. This article on the role of neutrophils, which play a significant role in maintaining inflammation in patients with atherosclerosis in combination with periodontitis, somewhat opens the veil of unexplored problems.
Атеросклеротические сердечно-сосудистые заболевания, пародонтит, нейтрофилы, провоспалительтные цитокины, гиперурикемияAtherosclerotic cardiovascular disease, periodontitis, neutrophils, pro-inflammatory cytokines, hyperuricemiaAterosklerotik yurak-qon tomir kasalliklari, paradontit, neytrofillar, yallig'lanishga qarshi sitokinlar, giperurikemiya
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