Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Ҷилди 8 № 4 (2023)
EVALUATION OF THE RESULTS OF THE TREATMENT OF NON-SPECIFIC ULCERATIVE COLITIS WITH THE APPLICATION OF PLASMAPHERESIS
ШОДМОНОВ Акбар Акрамович, КУРБАНИЯЗОВ Зафар Бабажанович, АСКАРОВ Пулат Азадович
Аннотатсия
Objective: Improving the results of treatment of steroid-dependent and steroid-resistant forms of ulcerative colitis. Methods: The study is based on the results of treatment of 105 patients with nonspecific ulcerative colitis with hormone-resistant and hormone-dependent forms, admitted to the surgical departments of the multidisciplinary clinic of Samarkand State Medical University in the period from 2012 to 2021. Results: In patients of the main group on the background of plasmapheresis, we received a complete response in 30 (64%) of 47 patients, an incomplete response in 15 (32%) patients, a partial response in 2 (4%) patients. In patients of the control group, the results of treatment during these periods were significantly worse than in patients of the main group. Conclusions: The positive dynamics of general clinical, laboratory parameters and endoscopic picture in patients with steroid - dependent and steroid - resistant forms of ulcerative colitis when using for their treatment a course of plasmapheresis with indirect electrochemical detoxification of blood plasma with additional ozonation indicates its effectiveness in stopping the exacerbation of the disease.
неспецифический язвенный колит, гормональная резистентность, гормональная зависимость, плазмаферезulcerative colitis, hormonal resistance, hormonal dependence, plasmapheresisnospetsifik yarali kolit, gormonal qarshilik, gormonal qaramlik, plazmaferez
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