Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 9-том 1-нөмір (2024)
ENDOSCOPIC REMISSION OF CLINICAL STEROID-DEPENDENT AND STEROID-RESISTANT FORMS OF NON-SPECIFIC ULCERATIVE COLITIS DURING COMPLEX TREATMENT WITH PLASMAPHERESIS
ШОДМОНОВ Акбар Акрамович, КУРБАНИЯЗОВ Зафар Бабажанович, АСКАРОВ Пулат Азадович
Аңдатпа
The work analyzed clinical material based on the results of a comprehensive examination and treatment of 102 patients with a confirmed diagnosis of ulcerative colitis. The positive dynamics of general clinical, laboratory parameters and endoscopic picture in patients with steroid-dependent and steroid-resistant forms of ulcerative colitis when a course of extracorporeal plasmapheresis is used for their treatment indicates its effectiveness in stopping the exacerbation of the disease. Despite the use of minimal doses of corticosteroids during plasmapheresis sessions, compared with standard therapy, patients with steroid-dependent and steroid-resistant forms of ulcerative colitis achieve remission more often (from 22% to 96%), complications from long-term use are significantly reduced corticosteroids, the possibility of complete abolition of maintenance therapy has been achieved, which ultimately leads to an improvement in the quality of life of this category of patients.
Неспецифический язвенный колит, стероид -зависимые и стероид - резистентные формы, плазмаферезNonspecific ulcerative colitis, steroid-dependent and steroid-resistant forms, plasmapheresisNonspesifik yarali kolit, steroidga bog'liq va steroidga chidamli shakllar, plazmaferez
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