Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 9 Issue 2 (2024)
ASSESSMENT OF THE SAFETY OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN PATIENTS WITH HIV INFECTION
АЧИЛОВА Матлюба Мирхамзаевна, ШОДИЕВА Дилафруз Абдужалоловна
Abstract
In this study, we investigated the safety of highly active antiretroviral therapy in HIV-infected patients. It is shown that as a result of the ineffectiveness and / or as a result of side effects of this therapy in 10.6% cases discontinued therapy performed or replacement regimens. One side effects of antiretroviral drugs - anemia occurs in 20.0% of HIV-infected patients and is often encountered when using regimens, containing azidotividin (AZT). In 8.5% of cases, the procedure has been changed due to the development of diarrheal syndrome. In addition, as the side effects of antiretroviral drugs developed lipodystrophy, peripheral neuropathy, and an increase of alanineaminotransferase activity.
inson immunitet tanqisligi virusi, yuqori faol antiretrovirus terapiya, virus yuklamasi, nukleotid va nukleozid bo'lmagan teskari transkriptaza inhibitorihuman immunodeficiency virus, highly active antiretroviral therapy, viral load, nucleotide and non-nucleoside reverse transcriptase inhibitorinson immunitet tanqisligi virusi, yuqori faol antiretrovirus terapiya, virus yuklamasi, nukleotid va nukleozid bo'lmagan teskari transkriptaza inhibitori
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