Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 9-tom 6-san (2024)
PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY
ЗУФАРОВА Шахноза Алимджановна, ЭШДАВЛАТОВ Илхом Эшниёзович
Annotaciya
The article presents data on the participation of "epithelial-mesenchymal transitions" in the pathogenetic mechanism of adhesion process development in women who have undergone gynecological surgeries. The pathogenetic mechanism of participation of matrix metalloproteinases-2 and 9 and tumor necrosis factor-a in the development of adhesions in women who have undergone gynecological surgeries has been proven. Their high levels indicate a destructive effect on the extracellular matrix, creating conditions for the development of adhesions due to the growth of fibrous tissue. The range of MMP-2 levels >400 pg/ml, MMP-9 >350 pg/ml and TNF-α >45 pg/ml in determining the risk of adhesions after gynecological surgeries has been established.
женщины, спаечная болезнь, патогенез, матриксные металлопротеиназы, фактор некроза опухолиwomen, adhesive disease, pathogenesis, matrix metalloproteinases, tumor necrosis factorayollar, bitishma kasallik, patogenez, matritsali metalloproteinazalar, o'simta nekrozi omili
Metadata derekkózi: jurnal OAI-PMH arxivi · Sindex tolıq mátindi saqlamaydı, derekkózge silteme beredi.