Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 9-tom 6-san (2024)
ANALYSIS OF MICROBIAL FLORA IN PATIENTS WITH COMPLICATED FORMS OF CHRONIC PURULENT OTITIS MEDIA
ХАТАМОВ Жахонгир Абруевич, АМОНОВ Шавкат Эргашевич
Annotaciya
Despite significant progress in prevention, diagnosis and treatment, chronic otitis media remains one of the most common and dangerous diseases among the population of the planet. In otology practice, the problem of early diagnosis and effective treatment of patients with chronic otitis media with complications remains key. The aim of the study is to analyze the microbial flora of different parts of the middle ear in chronic purulent otitis media with complications, assess the sensitivity of these microorganisms to various antibiotics, and comparatively analyze the microflora of pathologically altered areas of the middle ear detected during surgery. A total of 114 patients with chronic purulent otitis media with various complications who were hospitalized over the past 10 years and underwent surgery were examined. Microbiological methods included studying the species composition of microflora from the middle ear. After species identification of the isolated microflora, its sensitivity to antibiotics of various groups was studied. As a result of bacteriological examination it was established that in the etiological structure of chronic purulent otitis media complications the predominant microorganisms are gram-positive pyogenic cocci (golden and epidermal staphylococci), as well as non-fermenting rods (pseudomonas aeruginosa). In microbial associations yeast and mold fungi of the genus Aspergillus spp., Candida spp. and Mucor spp. were found. Obligate anaerobic microorganisms were less common, while peptostreptococci dominated among them. During the study the greatest sensitivity of microbes was established to cephalosporins (cefuraxime, ceftriaxone, cefotaxime) and fluoroquinolones (ciprofloxacin). Based on this, the treatment of patients was carried out using 2nd and 3rd generation cephalosporins in combination with fluoroquinolones locally, as well as antifungal drugs.
хронический гнойный средний отит, мастоидит, лабиринтиты, менингит, абсцессchronic purulent otitis media, mastoiditis, labyrinthitis, meningitis, abscesssurunkali yiringli o'rta otit, mastoidit, labirintit, meningit, xo'ppoz
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