Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Ҷилди 10 № 1 (2025)
ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS
РИЗАЕВ Жасур Алимжанович, ГАЙБУЛЛАЕВ Эльбек Азизбекович, АКРАМОВА Нозима Акрамовна, ПУСТОВЕТОВА Мария Геннадьевна
Аннотатсия
Aggressive periodontitis (AP) is a severe form of periodontal disease characterized by rapid tissue loss and significant inflammatory response. Immune mechanisms play a crucial role in the pathogenesis of AP, particularly through the activity of cytokines — mediators of inflammation that regulate the immune response and influence the progression of the disease. Studying the cytokine profile provides a deeper understanding of the pathogenesis of AP and aids in developing effective approaches for its diagnosis and treatment. This study aimed to investigate the levels of cytokines IL-1β, IL-4, and TNF-α in the gingival crevicular fluid of patients with different forms of AP.
Агрессивный пародонтит, профиль цитокинов, жидкость десневой борозды, медиаторы воспаленияAggressive periodontitis, cytokine profile, gingival crevicular fluid, inflammation mediators
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