Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 10-том 2-нөмір (2025)
RADIOLOGICAL SEMIOTICS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN TYPE II DIABETES MELLITUS
ТУРДУМАТОВ Жамшед Анварович, СОБИРОВА Нилуфар
Аңдатпа
Introduction: Chronic obstructive pulmonary disease (COPD) combined with type 2 diabetes mellitus (T2DM) is a complex clinical condition characterized by mutual aggravation of pathological processes, leading to a worse prognosis and lower quality of life. Identifying specific radiological signs helps improve early diagnosis. Methods: A total of 75 patients were examined and divided into three groups: I — COPD + T2DM (40 patients), II — COPD without diabetes (20), III — diabetes only (15). Methods included conventional radiography, multislice computed tomography (MSCT), and spirometry. Results: Patients with COPD and T2DM showed more severe symptoms (dyspnea — 75%, bronchial wall thickening — 80%). MSCT revealed reduced lung parenchyma transparency, especially in the upper lobes. Distinct microvasculopathy signs were observed: vascular dilation, "coral-like" deformation, and peribronchial changes. Emphysema and bronchiectasis were more frequent in the comorbid group. Discussion: COPD with type 2 diabetes leads to intensified lung morphology changes, including small airway and vascular damage. MSCT demonstrated high sensitivity (95%) and specificity (93.8%) for detecting structural abnormalities and is recommended for early-stage diagnostics in this patient group.
ХОБЛ, сахарный диабет 2 типа, рентгенологическая диагностика, МСКТ, микроваскулопатияCOPD, type 2 diabetes mellitus, radiological diagnosis, MSCT, microvasculopathySO‘OK, 2-tip qandli diabet, rentgenologik tashxis, MSKT, mikroangiopatiya
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