Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 10-том 4-сан (2025)
EVALUATION OF THE ROLE OF POLYMORPHIC GENES MMP-9 AND TIMP-1 IN MYOCARDITIS CAUSED BY SARS-COV-2
АХМЕДОВА Гулчехра Абдуллаевна, ШУКУРOВА Дилoрoм Баxoдирoвна
Аннотация
Current evidence suggests that MMP and TIMP gene polymorphisms may have a significant impact on the degree of inflammation and structural changes in the myocardium during viral infections, including COVID-19. However, the results of studies remain contradictory due to differences in study groups, methodologies, and evaluation criteria. In addition, most of the studies have focused on general aspects of inflammation in myocarditis, and the exact mechanisms associated with genetic variants in the MMP and TIMP genes are poorly understood.
коронавирусная болезнь 2019, вирус тяжелого острого респираторного синдрома, матриксные металлопротеиназ, тканевые ингибитор матриксных металлопротеиназcoronavirus disease 2019, severe acute respiratory syndrome virus, matrix metalloproteinas, tissue inhibitor of matrix metalloproteinasкоронавирус касаллиги 2019, оғир ўткир респиратор синдром вируси, матрикс металлопротеиназа, матрикс металлопротеиназа тўқима ингибитори
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