Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 10 Issue 4 (2025)
COMPARATIVE ANALYSIS OF PROSTATE SPECIFIC ANTIGEN LEVEL AND PROSTATE VOLUME WITH OVERACTIVE BLADDER IN PATIENTS WITH PROSTATE CANCER
ТИЛЛЯШАЙХОВ Мирзаголиб Нигматович, ХАККУЛОВ Эркин Бекмирзаевич, АЛИМОВ Жалолиддин Усмонхон угли
Abstract
In relation to prostate cancer prevention, the USPSTF-(UNITED STATES PREVENTIVE SERVICES TASKFORCE) task force recommends prostate-specific antigen screening for men aged 55-69 years, seeing a potential benefit in reducing mortality from this type of cancer. However, for men older than 70 years of age, the efficacy of screening appears less convincing. Prostate cancer is traditionally diagnosed by performing a finger rectal examination and prostate-specific antigen blood levels, followed by biopsy under the supervision of transrectal ultrasound. Androgen deprivation therapy alone has been shown to be associated with an increased risk of urinary incontinence compared with active surveillance. Some Asian prospective studies have reported improvement in lower urinary tract symptoms in prostate cancer patients treated with androgen deprivation therapy, with a primary focus on prostate volume reduction and improved uroflowmetry. The data of the study support the hypothesis that the introduction of complex therapy, including medication, exercise and, if necessary, androgen deprivation therapy, can significantly enhance the effectiveness of treatment of prostate cancer and overactive bladder syndrome. Not only has there been a decrease in prostate specific antigen levels and a reduction in prostate volume, but also an improvement in the overall health of patients. In particular, the decrease in the levels of prostate specific antigen and prostate volume indicates the positive dynamics of therapy, which is especially noticeable in groups with a complex approach to treatment.
Рак простаты, простатического специфического антигена, трансректальная ультразвуковая биопсия, андроген-депривационная терапияProstate cancer, prostate specific antigen, transrectal ultrasound biopsy, androgen deprivation therapyProstata bezi saratoni, prostate spesifik antigen, transrektal ultratovush biopsiyasi, androgenlardan mahrum qilish terapiyasi
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