Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 10 Issue 4 (2025)
EFFECT OF CHRONIC STRESS ON GENERATIONAL HYPOCAMP MORPHOLOGY
ХОШИМОВ Бобир Лухмонович, Куйланова Бахтиёра Базарбаевича
Abstract
This article examines the impact of chronic stress on the morphology of the hippocampus. The study compares the hippocampal structure and developmental dynamics of laboratory rat offspring born to stressed mothers with those in a control group. The results indicate that offspring exposed to stress exhibit a reduction in hippocampal neurocytes, vacuolization of the cytoplasm, changes in nuclear and cytoplasmic size, as well as neurocyte lysis. Additionally, the body weight of stressed rat offspring was found to be lower than that of the control group. The obtained data suggest that stress may have a negative impact on hippocampal structure.
стресс, гиппокамп, нейроциты, морфология, нейрогенез, патологические изменения, лабораторные крысы.stress, hippocampus, neurocytes, morphology, neurogenesis, pathological changes, laboratory rats.stress, gipokamp, neyrotsitlar, morfologiya, neyrogenez, patologik oʻzgarishlar, laborator kalamushlar
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