Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 10-том 4-сан (2025)
MORPHOLOGICAL CHANGES IN THE KIDNEYS DURING GESTATIONAL PYELONEPHRITIS IN THE SECOND AND THIRD PREGNANCIES
ТОЖИБОЕВ Темур Топволди угли, МАХКАМОВ Носиржон Жураевич
Аннотация
This study investigates the morphological alterations in kidney tissues of women with gestational pyelonephritis during the second and third pregnancies. Histopathological analysis revealed pronounced inflammation in the tubulointerstitial zone, dystrophic and destructive changes in nephrons, and pathological vascular modifications. Acute inflammatory processes were more prevalent during the second pregnancy, whereas the third pregnancy exhibited greater signs of fibrosis and chronic progression. These differential morphological patterns are likely associated with immunological and hormonal shifts specific to each pregnancy stage. The findings underscore the importance of early diagnosis and the development of individualized treatment strategies for gestational pyelonephritis.
гестационный пиелонефрит, вторая беременность, третья беременность, патоморфология, воспаление, фиброз, почечная ткань, нефрит, иммунные изменения.gestational pyelonephritis, second pregnancy, third pregnancy, pathomorphology, inflammation, fibrosis, renal tissue, nephritis, immune changesгестацион пиелонефрит, иккинчи ҳомиладорлик, учинчи ҳомиладорлик, патоморфология, нефрит, яллиғланиш, фиброз, буйрак тўқимаси, иммун ўзгаришлар.
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