Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 10-том 5-сан (2025)
MORPHOLOGICAL AND MORPHOMETRIC CHARACTERISTICS OF BONE TISSUE IN ALLOXAN-INDUCED OSTЕOPATHY AND ITS CORRECTION
ХАСАНОВ Азиз Батирович, ЮСУПОВ Шухрат Абдурасулович
Аннотация
The article presents the results of morphological and morphometric analysis of bone tissue in rats with alloxan-induced diabetes and evaluates the effectiveness of various correction methods (calcium gluconate, sulfated glycosaminoglycans, and their combination). The study examined the trabecular bone structure, osteoblast and osteoclast activity, osteocyte density, trabecular thickness, and trabecular area. The findings demonstrate pronounced structural disturbances of bone tissue in diabetic osteopathy and partial restoration under monotherapy, with the most significant effect observed in combined treatment.
Морфометрия, остеобласты, остеокласты, трабекулярная структура, диабетическая остеопатияmorphometry, osteoblasts, osteoclasts, trabecular structure, diabetic osteopathymorfometriya, osteoblastlar, osteoklastlar, trabekulyar tuzilma, diabetik osteopatiya
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