Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Volume 11 Issue 1 (2026)
EVALUATION OF THE CLINICAL EFFICACY OF GLYCYRRHIZIC ACID IN PATIENTS WITH COVID-19
ФАЙЗУЛЛАЕВ Шерзод Кобилжон угли, ШАХАРОВ Дилшод Жура угли, ТУХТАЕВ Шохзод Эшмурод угли, ХУЖАМБЕРДИЕВ Содикжон Учкун угли, САМИБАЕВА Умида Хуршидовна
Abstract
A prospective study of 163 patients with the new coronavirus infection COVID-19, hospitalized in the Samarkand Regional Specialized Medical Center for the period 2020-2022, was conducted. The level of vascular endothelial growth factor (VEGF A) in the blood serum was studied using the enzyme-linked immunosorbent assay method. The results of the conducted studies on the pathogenetic significance of markers of endothelial dysfunction in COVID-19 associated pneumonia showed that the endothelial dysfunction marker VEGF-A reaches reliably high levels, having a strong correlation with inflammatory markers both during admission to hospital, as well as during the discharge period. In this regard, pathogenetic therapy, including drugs with anti-inflammatory, antioxidant, and antifibrogenic effects during the early recovery period of COVID-19, is highly advisable.
Covid 19 ассоциированная пневмония, глициризиновая кислота, фактор роста эндотелия сосудов (VEGF A), эндотелиальная дисфункцияCovid 19 associated pneumonia, glycyrrhizic acid, vascular endothelial growth factor (VEGF A), endothelial dysfunctionCovid 19 bilan bog'liq pnevmoniya, glitsirizin kislotasi, qon tomir endotelial o'sish omili (VEGF A), endotelial disfunktsiya
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