Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 11-том 2-нөмір (2026)
THE INFLUENCE OF GSTM1 GENETIC POLYMORPHISM ON THE DEVELOPMENT OF BRONCHIECTASIS
ХАМИДОВА Фарида Муиновна, НОРЖИГИТОВ Азамат Мусакулович
Аңдатпа
The article presents a comprehensive analysis of a retrospective, diagnostic study of bronchiectasis in the population of the Samarkand region. The inclusion and exclusion criteria of patients were carefully studied, which confirmed the validity of the selected study groups. Particular attention is paid to the comparative histological and genetic analysis of patients with bronchiectasis. Bronchiectasis is more common in the city of Samarkand, Urgut and Narpay districts. The disease is seasonal, reaching its peak in spring and autumn. For the study, the results of pathomorphological - general histological, histochemical and morphometric examination of the bronchi and lung segments of 48 patients who underwent lobectomy due to bronchiectasis, as well as the results of laboratory biopsies (blood) to study the mutation of the GSTM1 gene polymorphism (dell) from 60 patients with bronchiectasis were studied.
бронхоэктазия, GSTM1, патоморфологияBronchiectasis, GSTM1, pathomorphologyBronxoektaz, GSTM1, patomorfologiya
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