Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali 11-tom 2-san (2026)
ERYTHEMA MULTIFORME EXUDATIVE IN THE ORAL CAVITY
ҲАЙИТОВА Меҳригул Алижон қизи, РАЖАБОВ Отабек Асрорович
Annotaciya
Objective:To increase the clinical effectiveness of treatment of erythema multiforme of the oral cavity by developing and implementing a comprehensive therapeutic and hygienic algorithm for local therapy. Materials and methods. 123 patients with MEE affecting the oral cavity aged from 20 to 60 years were under observation, 68 (55.3%) of them were women and 55 (44.7%) men. All patients were randomly assigned to the main group (74 people), which received a developed complex of local treatment, and the control group (49 people), where standard local therapy was performed. Results. The oral form of MEE is characterized by a combination of facial skin rashes and erosive and ulcerative lesions in the oral cavity. All patients had multiple painful erosions on the mucous membrane of the lips, cheeks, tongue and palate, covered with fibrinous plaque. The red border of the lips was affected in 78% of cases, often with the formation of bloody crusts and cracks. Patients complained of intense pain and burning in the mouth, inability to eat properly, hypersalivation and decreased taste sensations. In 46% of cases, concomitant skin elements (spots, papules) on the face and trunk were recorded. The general condition during the exacerbation period was characterized by weakness, subfebrility; 12% of patients had prodromal symptoms (malaise, headache) 1-2 days before the rash. Conclusion: The introduction of complex local therapy into clinical practice makes it possible to achieve a faster and more sustainable cure of multiform exudative erythema of the oral cavity. The data obtained substantiate the need to pay attention to the condition of the oral cavity in the treatment of MEE and actively correct local disorders (inflammation, microbial imbalance, dryness of the mucous membrane) along with systemic treatment. The proposed algorithm can be recommended as an addition to the standard protocols of oral MEE therapy to increase the effectiveness and shorten the rehabilitation time of patients.
многоформная экссудативная эритема; полость рта; местное лечение; иммунитет слизистой; качество жизниerythema multiforme; oral mucosa; local therapy; mucosal immunity; quality of lifeko’p shaklli ekssudativ eritema; og'iz bo'shlig'i; mahalliy davolash; shilliq qavat immuniteti; hayot sifati
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