Вестник Ассоциации пульмонологов Центральной Азии Volume 9 Issue 4 (2025) · pp. 23-27
TREATMENT OF MULTIDRUG-RESISTANT PULMONARY TUBERCULOSIS AND OPTIMIZATION OF TREATMENT EFFICACY
Teshayev S.J., Yitmasova T.D., Usmonov I.H.
Abstract
Multidrug-resistant tuberculosis (MDR-TB) remains a critical global health challenge, necessitating the development of novel strategies to optimize treatment outcomes. Morphological characteristics of the lungs in patients with MDR-TB provide crucial insights into disease progression and therapeutic responses. Among the various adjunctive therapeutic approaches, thiotriazoline, a thiol-containing compound, has emerged as a promising candidate in enhancing the efficacy of treatment regimens. This article reviews the morphological alterations associated with MDR-TB and explores the role of thiotriazoline in pathogenetic therapy, highlighting its potential in optimizing treatment efficacy.
lung morphology, treatment optimization, histopathology, drug resistance, statistical analysis
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