Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Volume 6 Issue 2 (2025)
CLINICAL AND PATHOGENETIC ASPECTS OF DEFEAT OF COGNITIVE DISODERS OF PATIENTS WITH CHRONIC KIDNEY DISEASE
Раимова Малика Мухамеджановна, Мурадова Малика Саидахроровна
Abstract
This article describes the clinical and pathogenetic features of defeat cognitive disorders of patients with chronic kidney disease (CKD). The study included 51 patients (21 men and 30 women) with CKD stages II-III, represented by parenchymal kidney diseases. For the main analysis, all patients were divided into 2 groups: group 1 included 20 people with CKD stages I and II; group 2 included 31 people with CKD stages III and IV. All patients underwent standard clinical, laboratory, neurological and instrumental examinations, including anamnesis collection, physical examination, clinical urine analysis, urine test for daily proteinuria, clinical and biochemical blood tests, echocardiography, daily blood pressure monitoring (DBPM), duplex scanning of common carotid arteries, MRI of the brain, assessment of cognitive functions. The frequency of detection and severity of cognitive dysfunctions in patients with CKD stages III-IV were significantly higher than in the group with CKD stages I-II (p<0.001). It has been demonstrated that CKD stages III-IV is an independent predictor of the development of CD (OR = 27.32, 95%CI 4.3-72.9, p<0.001).
хроническая болезнь почек, МРТ, ХБП, качество жизниchronic kidney disease, MRI, CRF, quality of lifeсурункали буйрак касаллиги, МРТ, СБК, ҳаёт сифати, когнитив бузилишлар
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