Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research 6-том 5-нөмір (2025)
NON-MOTOR SYMPTOMS OF PARKINSON'S DISEASE: CLINICAL SIGNIFICANCE AND THERAPEUTIC APPROACHES
Пулатова Дилёра Рустамовна, Саидвалиев Фаррух Саидакрамович, Хамидов Абдулахад Абдисаттарович
Аңдатпа
A total of 100 patients with Parkinson’s disease at stages I–III according to the Hoehn and Yahr scale, receiving outpatient care, were examined. All patients underwent comprehensive clinical-neurological and neuropsychological assessments with a focus on identifying non-motor symptoms. The NMSS, HADS, UPDRS, and PDQ-39 scales were used for evaluation. A comparative observation of the effectiveness of standard therapy and therapy with the addition of pramipexole was conducted. Patients receiving pramipexole as part of combination therapy showed a more significant reduction in anxiety-depressive, autonomic, and cognitive impairments. Improvement in sleep and general psycho-emotional status was also observed.
болезнь Паркинсона, немоторные симптомы, прамипексол, когнитивные нарушения, депрессия, вегетативная дисфункция, качество жизниParkinson’s disease, non-motor symptoms, pramipexole, cognitive impairment, depression, autonomic dysfunction, quality of lifeПаркинсон касаллиги, немотор симптомлар, прамипексол, когнитив бузилишлар, депрессия, вегетатив дисфункция, ҳаёт сифати
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