Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Том 6 № 5 (2025)
SEROTONERGIC MECHANISMS IN THE DEVELOPMENT OF LEVODOPA-INDUCED MOTOR AND NON-MOTOR DISORDERS IN PARKINSON’S DISEASE
Саидвалиев Фаррух Саидакрамович, Пулатова Дилёра Рустамовна, Хамидов Абдулахад Абдисаттарович
Аннотация
150 patients were examined with Parkinson’s disease. All participants underwent a comprehensive clinical, neurological, and neuropsychological evaluation, including measurement of serotonin and dopamine levels in blood plasma. Most patients showed a reduced level of serotonin, while dopamine levels remained within normal limits or were elevated. Lower serotonin levels were associated with more pronounced non-motor symptoms, particularly depression, anxiety, and cognitive impairment.
болезнь Паркинсона, серотонин, дофамин, плазма крови, немоторные симптомы, когнитивные нарушенияParkinson’s disease, serotonin, dopamine, blood plasma, non-motor symptoms, cognitive impairmentПаркинсон касаллиги, серотонин, дофамин, қон плазмаси, номотор симптомлар, когнитив бузилишлар
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