Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research 6-jild 5-son (2025)
PREDICTION OF PAIN SYNDROME IN POSTHERPETIC NEURALGIA BASED ON CLINICAL SYMPTOMS AND BLOOD BIOMARKERS
Хайдарова Дилдора Кадировна, Сулаймонов Муроджон Насирович
Annotatsiya
Postherpetic neuralgia (PHN) represents one of the most severe complications of herpes zoster, characterized by persistent pain syndrome that significantly reduces patients' quality of life. Traditional approaches to predicting PHN development were based predominantly on clinical risk factors such as age, severity of the acute phase, and lesion localization. However, modern studies demonstrate the necessity of an integrated approach, including analysis of biomarkers of inflammation, neurodegeneration, and pain sensitivity for more accurate prediction of disease course. The aim of the study is to develop a comprehensive prognostic model for pain syndrome development in PHN based on a combination of clinical parameters and laboratory blood biomarkers.
постгерпетическая невралгия, болевой синдром, биомаркеры, прогнозирование, воспалительные цитокины, нейропептиды, опоясывающий лишай, хроническая больpostherpetic neuralgia, pain syndrome, biomarkers, prediction, inflammatory cytokines, neuropeptides, herpes zoster, chronic painпостгерпетик невралгия, оғриқ синдроми, биомаркерлар, прогнозлаш, яллиғланиш цитокинлари, нейропептидлар, қайнатма қотури, сурункали оғриқ
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