Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Volume 6 Issue 6 (2025)
NEUROLOGICAL AND COGNITIVE IMPAIRMENTS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASSOCIATIONS WITH CEREBRAL HEMODYNAMICS AND NEUROIMAGING FINDINGS
Уринов Мусо Болтаевич, Тулаев Мирзохид Жалолович
Abstract
This study investigated neurological and cognitive alterations in 120 patients with different stages of COPD using clinical, neuropsychological assessments, transcranial Doppler ultrasonography, and MRI. Cognitive decline (attention and frontal dysfunction), impaired cerebral perfusion, and diffuse white matter changes were observed, with the most pronounced abnormalities at stages III–IV. The findings highlight the importance of early screening and multidisciplinary management of neurological complications in COPD patients to improve clinical outcomes and quality of life.
ХОБЛ, когнитивные нарушения, неврологический статус, церебральная гемодинамика, МРТ, транскраниальная допплерография, качество жизниChronic obstructive pulmonary disease, cognitive dysfunction, neurological impairment, cerebral hemodynamics, MRI, transcranial Doppler, quality of lifeO‘pkaning surunkali obstruktiv kasalligi, nevrologik buzilishlar, kognitiv disfunktsiya, miya gemodinamikasi, MRT, transkranial doppler, hayot sifati
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